The San Francisco VA Health Care System is recruiting for an advanced two-year Post-Doctoral Fellowship Program in Epidemiology with a focus on using data science and genetic approaches to solve new challenges in cognitive and brain health research. The fellowship is associated with the Sierra Pacific Mental Illness Research Education and Clinical Center (MIRECC; VISN 21) and affiliated with the University of California, San Francisco (UCSF).
The primary goal of the program is to train fellows with a doctoral degree in epidemiology, statistical genetics, bioinformatics, biostatistics, computer science, data science or similar quantitative field to become skilled investigators for advancing our understanding of Alzheimer’s disease, dementia, and cognitive aging. By applying cutting-edge statistical genetic and genetic epidemiological approaches to large genetic & phenotypic datasets, potential projects will focus on the causal pathways that underly the development of Alzheimer’s disease and related dementias (ADRD) and may include (1) identifying causal risk factors for ADRD using genetic correlations, polygenic risk scores and mendelian randomization; (2) understanding the role of mitochondrial genomics in ADRD pathogenesis; and (3) evaluating ancestry-specific effects of AD genetic variants on AD endophenotypes. The successful candidate will have the opportunity to work on large scale genomic and phenotypic datasets to address research questions and receive training in bioinformatic concepts and computational methods. Fellows will be responsible for driving an original research agenda aligned with the lab’s overall research goals while also gaining skills and training to become an independent investigator.
Under the guidance of Fellowship Director, Dr. Kristine Yaffe, and Co-Director, Dr. Shea Andrews, the candidate will have the opportunity to collaborate with investigators and participate in didactic sessions. Additional faculty mentors are affiliated with the SFVAMC services for Mental Health, Medicine, Neurology, and Radiology, the UCSF/ SFVAMC Center for Population Brain Health, the UCSF Departments of Psychiatry and Behavioral Sciences, Neurology, Epidemiology/Biostatistics, Precision Medicine, Neuroscience, and the Global Brain Health Institute.
We are a team of multidisciplinary researchers, dedicated to advancing brain heath across the lifespan. We emphasize population-based research methods to identify risk and protective factors for dementia, cognitive aging, and brain health, and to optimize cognitive and emotional brain health in aging. The expertise of our faculty spans the fields of genetics, epidemiology, neurology, and psychiatry. Please see faculty webpages (profiles.ucsf.edu) and CPBH website (popbrain.ucsf.edu) for more details. The fellowship is funded by the Office of Academic Affiliations (OAA), Department of Veterans Affairs (VA).
Faculty:
- Kristine Yaffe, MD, Fellowship Director, board-certified psychiatrist and neurologist (https://yaffe.ucsf.edu/)
- Shea Andrews, PhD, Co-Director, genetic epidemiologist
- Raquel Gardner, MD, behavioral neurologist
- Yue Leng, PhD, epidemiologist
- Willa Brenowitz, PhD, epidemiologist
- Erica Kornblith, PhD, neuropsychologist
- Dugyu Tosun, PhD, engineer
- Eric Vittinghoff, PhD, biostatistician
- Jennifer Yokoyama, PhD, behavioral geneticist
- John Boscardin, PhD, biostatistician
- Deborah Barnes, PhD, epidemiologist
To apply, please email the following to Tina Hoang (administrative assistant) [email protected]
- Letter of interest detailing your research experience, interests, career goals, and proposed faculty mentor(s) from list above
- CV
- 3 letters of recommendation
The application deadline is November 15, 2023. Applications submitted after that date may be considered until the position is filled.